ThroughoutHouse’s eight seasons and 177 episodes, the doctors of Princeton–Plainsboro Teaching Hospital solve many bizarre cases and experience a lot of trauma and drama, but the series could have gone without some frustrating and heartbreaking storylines. David Shore’s medical drama follows Hugh Laurie’s Dr. Gregory House, the narcissistic and cynical Head of the Department of Diagnostic Medicine at PPTH.House and his team of doctorswork to diagnose patients with mysterious illnesses and ailments every episode. However, outside of work,theHousecharacters have various problems, many of which contribute to some plots that are better off forgotten.
Housepremiered on June 07, 2025, and ended on June 17, 2025.
Given thatHouselasted as long as it did on Fox, the TV show’s positives outweigh its negatives. From House’s relationship with Dr. James Wilson toHouse’s riveting medical cases, the series truly shines when it’s at its best. Unfortunately,House’s worst storylines sometimes stand out from the good ones,especially when they are stretched out over the course of multiple episodes. The medical drama is very well-made overall, but one can’t help but cringe or look away from the screen during a handful of points in the show.
10Cameron’s Infatuation With House
Cameron Was Obsessed With House, While He Never Loved Her
House’s dynamic with Jennifer Morrison’s Dr. Allison Cameron (an immunologist on House’s team) is undoubtedly one of the strangest relationshipsin the Fox medical drama. For starters, House is Cameron’s boss, and he is older than her. Consequently, the power dynamics are automatically imbalanced, which makes it uncomfortable to watch House and Cameron’s relationship play out on the small screen. Additionally, Cameron is obsessed and infatuated with House. Meanwhile,Hugh Laurie’sHousecharacternever reciprocates Cameron’s feelings, and she consistently pushes House, oblivious to the fact that he will never want her.
I’m Pretty Sure Hugh Laurie Broke Character In This House Scene And No One Noticed It
Hugh Laurie’s performance in House is one of the most immersive in network TV history, yet one scene highlights a potential and surprising mistake.
Cameron’s supposed love for her boss isa weird and bothersomeHousestorylinethat never fails to make most viewers cringe. It’s obvious that Cameron is attracted to House because he is a broken man. She doesn’t love him — she loves the person she thinks he can be. Unfortunately,this one-sided attraction between Cameron and House plays out for way too long inHousebefore Cameron finally moves on, making it difficult for one to ignore and forget despite desperately wanting to.
9Chase Kissing A Patient Who Was A Child
A Nine-Year-Old With Terminal Cancer Asked Chase To Kiss Her
If a person were to tell someone who had never seen anepisode ofHousethatone of the (adult) main characters kissed their nine-year-old patient on the lips because she asked him to,they either wouldn’t believe them or would likely be a bit (or a lot) disturbed. Both options are understandable. However, that’s exactly what happened to Dr. Robert Chase inHouseseason 2, episode 2.
Given that Chase is an adult and Andie’s doctor, and she is nine and his patient, it’s obvious why this storyline is amongHouse’s worst.
Andie (played bySasha Pieterse fromPretty Little Liars), who was diagnosed with alveolar rhabdomyosarcoma is admitted to the hospital when she starts having hallucinations unrelated to her cancer. House’s team solves the problem and fixes it, but thatwon’t stop the cancer from eventually killing Andie.So, Andie tells Chase about her fear of never getting to kiss a boy and asks him to do it. He objects at first but eventually relents. Given that Chase is an adult and Andie’s doctor, and she is nine and his patient, it’s obvious why this storyline is amongHouse’s worst.
8Hiring Samira Terzi & Firing Her 1 Episode Later
Terzi Quit Her Job For House
House meets Dr. Samira Terzi, a staff doctor working for the CIA, duringHouseseason 4, episode 6, when he is recruited to help diagnose a CIA operative. From the beginning, it’s clear thatHouse is attracted to Samira.She consistently turns him down (including a job offer), despite his persistence. But by the hour’s end, Samira accepts a position on House’s team at Princeton–Plainsboro, which he would soon come to regret inthe medical procedural showHouse.
Samira begins working at Princeton–Plainsboro during the next episode, and by its end, she is gone. House realizes that her medical skills are subpar, and his attraction to her clouds his judgment. So, House lets Samira go one episode after convincing her to quit her CIA job. Bold as ever, House still asks her out, and she just walks away from him.Samira’s storyline is quite frustrating as it is unnecessary,especially since she is only around for two episodes. It undoubtedlyshows how much of a jerk House is, but it’s also amoment that could make viewers quit watchingHouse.
7Amber’s Death
Amber Died During The House Season 4 Finale
As a disclaimer,the two-partHouseseason 4 finale is among the show’s best episodes(if not,thebest episodes). However, that doesn’t make them any less heartbreaking or stop some from wishing they never happened. Season 4 introduces Dr. Amber Volakis as one of the candidates for House’s team, and from the get-go, she and House don’t get along. He nicknames Amber “Cutthroat B*tch” and ultimately doesn’t offer her a position. Nevertheless,Amber sticks around because she starts dating Wilson,much to House’s dismay.
Amber’s time on the Fox medical drama is finite, though, as she dies by the end of the season 4 finale. The first part of the finale featuresHouse trying to recall his memories of a bus crashbecause he has a fleeting memory of one of the passengers exhibiting signs of an illness before the crash. House eventually deduces that it’s Amber, who is experiencing tachycardia at a nearby hospital.
The two-part finale is superb, but the heartbreak and tragedy resulting from Amber’s death are so significant that we wish theHousestoryline had never happened.
TheHousecharactersmove her to Princeton–Plainsboro where they discoverAmber took a heavy dose of amantadine before the crash, and the accident caused acute kidney injury.As a result, her kidneys can’t filter out the amantadine. There’s nothing they can do, and Ambersadly dies in theHouseepisodeas Wilson holds her. As mentioned above, the two-part finale is superb, but the heartbreak and tragedy resulting from Amber’s death are so significant that we wish theHousestoryline had never happened.
6Cuddy’s Relationship With Lucas
Cuddy Dated Lucas In House Season 6
Houseseason 5 introduces Lucas Douglas as a private investigator who House hires, but by the sixth season, Lucas becomes Dr. Lisa Cuddy’s boyfriend (and briefly fiancé). While Lucas is a fun and unique character, he has no business dating Cuddy.The twoHousecharacters have no chemistry,and it’s clear that the writers only pushed Cuddy and Lucas together to create more drama forHouse and Cuddy’s tumultuous love story.
Odette Annable
Dr. Jessica Adams
Lucas is enjoyable when he’s working as a private investigator, not when he’s being used as a tool to create a love triangle featuring himself, House, and Cuddy.Love triangles are wholly overrated on TVand are more infuriating than intriguing. Plus, it doesn’t help when one couple in a fictional love triangle doesn’t make any sense together (e.g. Cuddy and Lucas). Cuddy’s relationship with Lucas is just an unnecessary obstacle to her andHouse becoming a couplethat the Fox medical drama can do without.
5Cameron Settling For Chase & Then Getting Divorced Anyway
Cameron & Chase Divorced In House Season 6
Jennifer Morrison’s Cameron is, unfortunately, one of the most dislikedHousecharacters, and it’s partly due to her romantic storylines over the course of her time on the show. Cameron’s infatuation with House is frustrating, but so is her back-and-forth relationship with Chase. From the beginning, it’s obvious thatCameron and Chase make for a better couple than Cameron and House.In spite of that, Cameron still pursues House. She eventually lets go of House, though, and moves on to (or settles for) Chase. They marry during the season 5 finale, but it’s not long before they separate for good.
Chase undoubtedly likes Cameron more than Cameron likes him,which is partially what makes their relationship inHouseso disappointing. She has commitment issues that Chase can’t fix. So,Chase and Cameron officially get a divorce inHouseseason 6, episode 17, their marriage not lasting for even one season. The two characters have chemistry, making it easier to root for them. However, the way Chase and Cameron’s story plays out is quite aggravating overall. Their relationship is seemingly doomed from the start because it never makes any real progress concerning Chase and Cameron’s growth as individuals and as a couple.
4House Driving His Car Into Cuddy’s House
House & Cuddy’s Breakup Was Ugly
House driving his car into Cuddy’s house intheHouseseason 7 finaleis pretty much unanimously one of the show’s worst moments. He and Wilson go to Cuddy’s to return her hairbrush, and House is about to go inside when he sees Cuddy inside with another man and her family. House turns back around, gets in his car, and crashes into the house. It’s an overreaction, of course, but it’s alsoout of character for House.Yes, Hugh Laurie’s character has many problems, but even he wouldn’t drive his car into the home of someone he loves.
House driving his car into Cuddy’s house is so shocking that it’s hard to forget (no matter how much one wants to).
This officiallymarks the end of House and Cuddy’s relationship.His fit of jealous rage is unforgivable, andCuddy is never seen again inHouse. Lisa Edelstein wanted to leave the show, but there are better ways to write her out instead of formulating a horrifying scene that doesn’t make any sense. Ultimately, House driving his car into Cuddy’s house is so shocking that it’s hard to forget (no matter how much one wants to).
3Foreman & Thirteen’s Relationship
Foreman & Thirteen Didn’t Have Much Chemistry
Housefeatures numerous important relationships, but many were more frustrating than endearing, including Dr. Remy “Thirteen” Hadley and Dr. Eric Foreman’s. Thirteen is one of the candidates House hires to be a part of his new team in season 4, and Foreman seems to have an understanding of her that no one else does.Foreman and Thirteen start dating in season 5and break up in season 6. Despite their connection, Foreman and Thirteen have no chemistry.
Foreman and Thirteen’s relationship feels forced,making it one of the more dull ones in the Fox medical drama. Pushing the two together also feels unnecessary and proves to be more of a detriment to their characters than a benefit. In the end, it’s difficult to care about Foreman and Thirteen’s relationship inHouse, making their breakup insignificant in the grand scheme of the show.
It’s Unclear If Cameron Used The Sperm
BeforeHousebegan,Cameron was married to a man named Bob for six months before he died of thyroid cancer.Prior to his death, though, Cameron collected and froze his semen, which Chase later learns while he and Cameron are dating. She did so in the case that he died, and she wanted to have a baby. Cameron freezing her dead husband’s semen is certainly one of the more bizarre storylines, but it becomes frustrating when it’s used to drive a wedge between Cameron and Chase inthe medical drama TV show.
I Watched House’s First Episode In 2004 & This Is What I Got So Wrong About The Show
House season 1, episode 1, “Everybody Lies” hinted at the show’s potential, but I never predicted the medical drama would become as big as it did.
Additionally, Jennifer Morrison reprises her role as Cameron during House’s funeral intheHouseseries finale, and it’s shown that she is in a relationship and has a baby. Cameron’s new partner is likely the infant’s father. However,some can’t help but speculate that Cameron used her dead husband’s sperm to get pregnant.Whatever the case, it’s better to just forget about the strange storyline altogether.
1Wilson’s Cancer
Wilson Was Diagnosed With Stage II Thymoma
Similar to Amber’s death inHouseseason 4,Wilson’s cancer diagnosis is one of the show’s worst storylines because it’s so heartbreaking.Wilson is one of the best characters inHouse, and, as a result, many feel as if his stage II thymoma during the final season is unfair and unnecessary. Of course, cancer affects everyone. However, it doesn’t feel right to end the medical drama with Wilson’s impending death.
Housewas nominated for 13 Emmys over the course of its eight-year run, winning two — Outstanding Writing for a Drama Series for David Shore’s “Three Stories” in 2005 and Outstanding Directing in a Drama Series for Greg Yaitanes' “House’s Head” in 2008. Hugh Laurie also earned six Emmy nominations for Outstanding Lead Actor in a Drama Series for his performance as Dr. Gregory House.
Wilson’s cancer storyline draws out tremendous performances from both Hugh Laurie and Robert Sean Leonard, but the cost is too great. So,it’s easy to wish to forget about Wilson’s fate.Ultimately,Wilson undoubtedly deserves better than his ending inHouse, which includes his inevitable death (which is never shown onscreen but implied at the end of the finale).
House
Cast
House is a medical mystery drama in which the villain is typically a difficult-to-diagnose medical malady. It follows Dr. Gregory House (Hugh Laurie), a world-renowned disabled diagnostician with a notorious substance abuse issue. With his team of world-class doctors, House has built a reputation as one of the most brilliant doctors in the world - an especially impressive feat when taking into account that he rarely actually sees his patients.
